The biggest win in gambling history is still the famous \$39.7 million jackpot hit at the Excalibur Casino in Las Vegas back in 2003. That was from a \$100 Megabucks slot spin! Online casinos have also seen some massive wins recently. While playing on sites like Playzilla, you’ll come across progressive slots with huge prize pools — some players have even hit six or seven-figure wins. It just goes to show that with the right spin and a bit of luck, life-changing payouts are possible.