Hello! There are many Internet projects (commercial) that do not affect the Internet of things. I would advise you to pay attention to modern developments for custom applications. This option is often included by all companies that want to get their share of attracting online customers. Node.js fits perfectly with modern requirements. If you look at the leading companies, you can especially note Binary Studio -
https://binary-studio.com/custom-healthcare-software-development/ This is a combination of traditional quality programming using advanced technologies for the web sphere.